We read with great interest the work by Small Jr. et al. (
) about the outcomes of uterine perforations during cervical cancer brachytherapy procedure. Perforation was associated with increased risk of acute infection (13.6% versus 3.0% if no uterine perforation, p = 0.04). The local infections resolved without further complications or treatment delays. No increase in long-term complications or recurrence-free survival was detected. Taken in conjunction, these findings reassure that observation approach is safe after perforation if the patient remained asymptomatic.
- Small Jr., W.
- YS Kim
- C Joyce
- et al.
Uterine perforation during brachytherapy for cervical cancer: complications, outcomes, and best practices for forward treatment planning and management.
Brachytherapy. 2021; 20: 557-564
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- Uterine perforation during brachytherapy for cervical cancer: complications, outcomes, and best practices for forward treatment planning and management.Brachytherapy. 2021; 20: 557-564
- A phase III randomized trial of trans-abdominal ultrasound in improving application quality and dosimetry of intra-cavitary brachytherapy in locally advanced cervical cancer.Gynecol Oncol. 2021; 160: 375-378
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- Prevention of uterine perforation during intracavitary brachytherapy of cervical cancer.J Contemp Brachyther. 2021; 13: 167-171
- Radiation therapy for cervical cancer: executive summary of an ASTRO clinical practice guideline.Pract Radiat Oncol. 2020; 10: 220-234
Published online: December 31, 2021
Accepted: July 16, 2021
Received: July 11, 2021
© 2021 American Brachytherapy Society. Published by Elsevier Inc. All rights reserved.