Validation of MRI to US Registration for Focal HDR Prostate Brachytherapy

      High dose rate (HDR) prostate brachytherapy can achieve long-term disease control. Multiparametric Magnetic Resonance Imaging (mpMRI) allows identification of gross tumor (GTV) in order to boost or target lesions. However, a significant number of clinics are using ultrasound (US) as their planning imaging modality due to its low cost and real time capability; but can’t identify the position of the GTV. Therefore, a registration is needed between mpMRI and US images to accurately delineate the GTV. The goal of the study was to develop and validate a new 3D Slicer MRI to US registration module for focal HDR prostate brachytherapy treatment.
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