Radioembolization via yttrium-90 (90Y) microspheres enables selective internal radiotherapy (SIRT) for hepatic malignancies.
Even though careful planning of the procedure takes place, including pre-treatment
angiograms and technetium-99m labeled macroaggregated albumin (99mTc-MAA) SPECT, there is no standard for post-delivery imaging and dosimetry of the
microsphere distribution for treatment delivery verification. Recent studies have
reported utilizing the small positron yield of 90Y (32 ppm) to image patients with PET after their treatment to perform dosimetry analysis.
In this study, we compared results from a commercial dosimetry software—MIM Sureplan
(MIM Software, Cleveland, OH)—to a MATLAB-based program developed in-house for the
purpose of commissioning the software for clinical use.
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© 2017 Published by Elsevier Inc.
