Brachytherapy
Volume 8, Issue 4 , Pages 396-400 , October 2009

Clinical outcome of pathologic Stage IIA endometrial adenocarcinoma after intravaginal brachytherapy alone

  • Farzan Siddiqui

      Affiliations

    • Department of Radiation Oncology, Henry Ford Hospital, Detroit, MI
    • ,
  • Dina R. Ibrahim

      Affiliations

    • Department of Radiation Oncology, Henry Ford Hospital, Detroit, MI
    • ,
  • Ibrahim Aref

      Affiliations

    • Department of Radiation Oncology, Henry Ford Hospital, Detroit, MI
    • ,
  • Mei Lu

      Affiliations

    • Department of Biostatistics and Research Epidemiology, Henry Ford Hospital, Detroit, MI
    • ,
  • Woo Shin Kim

      Affiliations

    • Department of Gynecologic Oncology, Henry Ford Hospital, Detroit, MI
    • ,
  • Daniel Schultz

      Affiliations

    • Department of Pathology, Henry Ford Hospital, Detroit, MI
    • ,
  • Mohamed A. Elshaikh

      Affiliations

    • Department of Radiation Oncology, Henry Ford Hospital, Detroit, MI
    • Corresponding Author InformationCorresponding author. Department of Radiation Oncology, Henry Ford Hospital, 2799 West Grand Boulevard, Detroit, MI 48202. Tel.: +1-313-916-1015; fax: +1-313-916-3235.

Received 4 November 2008 ,Revised 24 February 2009 ,Accepted 2 April 2009.

References 

  1. Jemal A, Siegel R, Ward E, et al. Cancer statistics, 2008. CA Cancer J Clin. 2008;58:71–96
  2. Creasman WT, Odicino F, Maisonneuve P, et al. Carcinoma of the corpus uteri. FIGO 6th Annual Report on the Results of Treatment in Gynecological Cancer. Int J Gynaecol Obstet. 2006;95(Suppl. 1):S105–S143
  3. Ahmad K, Kim YH, Deppe G, et al. Radiation therapy in stage II carcinoma of the endometrium. Cancer. 1989;63:854–858
  4. Sartori E, Gadducci A, Landoni F, et al. Clinical behavior of 203 stage II endometrial cancer cases: The impact of primary surgical approach and of adjuvant radiation therapy. Int J Gynecol Cancer. 2001;11:430–437
  5. The NCCN . Clinical practice guidelines in oncology: Uterine neoplasms V. J Natl Compr Cancer Netw. 2008;ISS
  6. Eltabbakh GH, Moore AD. Survival of women with surgical stage II endometrial cancer. Gynecol Oncol. 1999;74:80–85
  7. Ayhan A, Taskiran C, Celik C, et al. The long-term survival of women with surgical stage II endometrioid type endometrial cancer. Gynecol Oncol. 2004;93:9–13
  8. Aalders J, Abeler V, Kolstad P, et al. Postoperative external irradiation and prognostic parameters in stage I endometrial carcinoma: Clinical and histopathologic study of 540 patients. Obstet Gynecol. 1980;56:419–427
  9. Creutzberg CL, van Putten WL, Koper PC, et al. Survival after relapse in patients with endometrial cancer: Results from a randomized trial. Gynecol Oncol. 2003;89:201–209
  10. Keys HM, Roberts JA, Brunetto VL, et al. A phase III trial of surgery with or without adjunctive external pelvic radiation therapy in intermediate risk endometrial adenocarcinoma: A Gynecologic Oncology Group study. Gynecol Oncol. 2004;92:744–751
  11. Alektiar KM, Venkatraman E, Chi DS, et al. Intravaginal brachytherapy alone for intermediate-risk endometrial cancer. Int J Radiat Oncol Biol Phys. 2005;62:111–117
  12. Ng TY, Nicklin JL, Perrin LC, et al. Postoperative vaginal vault brachytherapy for node-negative Stage II (occult) endometrial carcinoma. Gynecol Oncol. 2001;81:193–195
  13. Jolly S, Vargas C, Kumar T, et al. Vaginal brachytherapy alone: An alternative to adjuvant whole pelvis radiation for early stage endometrial cancer. Gynecol Oncol. 2005;97:887–892
  14. Solhjem MC, Petersen IA, Haddock MG. Vaginal brachytherapy alone is sufficient adjuvant treatment of surgical stage I endometrial cancer. Int J Radiat Oncol Biol Phys. 2005;62:1379–1384
  15. Nout RA, Putter H, Jürgenliemk-Schulz IM, et al. Vaginal brachytherapy versus external beam pelvic radiotherapy for high-intermediate risk endometrial cancer: Results of the randomized PORTEC-2 trial. J Clin Oncol. 2008;26(May 20 Suppl.):abstr LBA5503
  16. Cohn DE, Woeste EM, Cacchio S, et al. Clinical and pathologic correlates in surgical stage II endometrial carcinoma. Obstet Gynecol. 2007;109:1062–1067
  17. Harrell FE. Predicting outcomes: applied survival analysis and logistic regression. Charlottesville, VA: University of Virginia Book Store; 1997;p. 6.1–6.48

 Conflict of interest: The authors declare no conflict of interest with the material presented in the article.

 Presented at the 50th Annual Meeting of the American Society of Therapeutic Radiology and Oncology (ASTRO), Boston, MA, on 2008.

PII: S1538-4721(09)00246-3

doi: 10.1016/j.brachy.2009.04.001

Brachytherapy
Volume 8, Issue 4 , Pages 396-400 , October 2009

Article Tools

* Image Usage & Resolution