Brachytherapy
Volume 8, Issue 3 , Pages 304-308 , July 2009

Dosimetric outcomes in prostate brachytherapy: Is downsizing the prostate with androgen deprivation necessary?

  • Erin P. Gibbons

      Affiliations

    • Department of Urology, University of Pittsburgh Medical Center, Pittsburgh, PA
    • Department of Urology at the University of Toronto, Toronto, Canada
    • ,
  • Bruce L. Jacobs

      Affiliations

    • Department of Urology, University of Pittsburgh Medical Center, Pittsburgh, PA
    • Corresponding Author InformationCorresponding author. Department of Urology, University of Pittsburgh School of Medicine, 3471 Fifth Avenue, Pittsburgh, PA 15217. Tel.: +1-412-692-4100; fax: +1-412-692-4101.
    • ,
  • Ryan P. Smith

      Affiliations

    • Department of Radiation Oncology, University of Pittsburgh Medical Center, Pittsburgh, PA
    • ,
  • Sushil Beriwal

      Affiliations

    • Department of Radiation Oncology, University of Pittsburgh Medical Center, Pittsburgh, PA
    • ,
  • Komanduri Krishna

      Affiliations

    • Department of Radiation Oncology, University of Pittsburgh Medical Center, Pittsburgh, PA
    • ,
  • Ronald M. Benoit

      Affiliations

    • Department of Urology, University of Pittsburgh Medical Center, Pittsburgh, PA

Received 18 April 2008 ,Revised 31 October 2008 ,Accepted 3 November 2008.

References 

  1. D'Amico AV, Whittington R, Malkowicz SB, et al. Biochemical outcome after radical prostatectomy, external beam radiation therapy, or interstitial radiation therapy for clinically localized prostate cancer. JAMA. 1998;280:969–974
  2. Prestidge BR, Prete JJ, Buchholz TA, et al. A survey of current clinical practice of permanent prostate brachytherapy in the United States. Int J Radiat Oncol Biol Phys. 1998;40:461–465
  3. Nag S, Beyer D, Friedland J, et al. American Brachytherapy Society (ABS) recommendation for transperineal permanent brachytherapy of prostate cancer. Int J Radiat Oncol Biol Phys. 1999;44:789–799
  4. Stone NN, Stock RG. Prostate brachytherapy in patients with prostate volumes ≥50 cm3: dosimetric analysis of implant quality. Int J Radiat Oncol Biol Phys. 2000;46:1199–1204
  5. Wilson S. Downsizing and prostate cancer. Rev Urol. 2004;6(Suppl 7):S19–S24
  6. Lee WR. The role of androgen deprivation therapy combined with prostate brachytherapy. Urology. 2002;60(3 Suppl. 1):39–44
  7. Gibbons EP, Smith RP, Beriwal S, et al. Overcoming pubic arch interference with free hand needle placement in men undergoing prostate brachytherapy. Brachytherapy. 2009;8:74–78
  8. Nag S, Bice W, DeWyngaert K, et al. The American Brachytherapy Society recommendation for permanent prostate brachytherapy postimplant dosimetric analysis. Int J Radiat Oncol Biol Phys. 2000;46:221–230
  9. Stock RG, Stone NN, Tabert A, et al. A dose-response study for I-125 prostate implants. Int J Radiat Oncol Biol Phys. 1998;41:101–108
  10. Potters L, Cao Y, Calugaru E, et al. A comprehensive review of CT-based dosimetry parameters and biochemical control in patients treated with permanent prostate brachytherapy. Int J Radiat Oncol Biol Phys. 2001;50:605–614
  11. Quan AL, Ciezki JP, Reddy CA, et al. Improved biochemical relapse-free survival for patients with large/wide glands treated with prostate seed implantation for localized adenocarcinoma of prostate. Urology. 2006;68:1237–1241
  12. Kucway R, Vicini F, Huang R, et al. Prostate volume reduction with androgen deprivation therapy before interstitial brachytherapy. J Urol. 2002;167:2443–2447
  13. Potters L, Torre T, Ashley R, et al. Examining the role of neoadjuvant androgen deprivation in patients undergoing prostate brachytherapy. J Clin Oncol. 2000;18:1187–1192
  14. Ebara S, Manabe D, Kobayashi Y, et al. The efficacy of neoadjuvant androgen deprivation therapy as a prostate volume reduction before brachytherapy for clinically localized prostate cancer. Acta Med Okayama. 2007;61:335–340
  15. Beyer DC, McKeough T, Thomas T. Impact of short course hormonal therapy on overall and cancer specific survival after permanent prostate brachytherapy. Int J Radiat Oncol Biol Phys. 2005;61:1299–1305
  16. Sylvester J, Blasko J, Grimm P, et al. 125-Iodine/103-Palladium brachytherapy with or without neoadjuvant androgen ablation for early stage prostate cancer. Int J Radiat Oncol Biol Phys. 2000;48:310–311
  17. Sylvester J, Blasko JC, Grimm P, et al. The impact of short course androgen ablation on the biochemical progression-free survival of high-risk, localized prostate cancer patients managed with a combination of permanent interstitial brachytherapy and external beam radiation therapy. J Brachyther Int 2001. In press.
  18. Merrick GS, Butler WM, Wallner KE, et al. Androgen deprivation therapy does not impact cause-specific or overall survival in high-risk prostate cancer managed with brachytherapy and supplemental external beam. Int J Radiat Oncol Biol Phys. 2007;68:34–40
  19. Crook J, McLean M, Catton C, et al. Factors influencing risk of acute urinary retention after TRUS-guided permanent prostate seed implantation. Int J Radiat Oncol Biol Phys. 2002;52:453–460
  20. Crook J, Toi A, McLean M, et al. The utility of transition zone index in predicting acute urinary morbidity after 125I prostate brachytherapy. Brachytherapy. 2002;1:131–137
  21. Hinerman-Mulroy A, Merrick GS, Butler WM, et al. Androgen deprivation-induced changes in prostate anatomy predict urinary morbidity after permanent interstitial brachytherapy. Int J Radiat Oncol Biol Phys. 2004;59:1367–1382
  22. Merrick GS, Butler WM, Lief JH, et al. Temporal resolution of urinary morbidity following prostate brachytherapy. Int J Radiat Oncol Biol Phys. 2000;47:121–128
  23. Stock RG, Kao J, Stone NN. Penile erectile function after permanent radioactive seed implantation for treatment of prostate cancer. J Urol. 2001;165:436–439
  24. Potters L, Torre T, Fearn PA, et al. Potency after permanent prostate brachytherapy for localized prostate cancer. Int J Radiat Oncol Biol Phys. 2001;50:1235–1242

PII: S1538-4721(08)00680-6

doi: 10.1016/j.brachy.2008.11.009

Brachytherapy
Volume 8, Issue 3 , Pages 304-308 , July 2009

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