Brachytherapy
Volume 8, Issue 1 , Pages 9-13 , January 2009

MammoSite® accelerated partial breast irradiation: A single-institution outcomes analysis with 2 years of followup

  • Marsha Haley

      Affiliations

    • Department of Radiation Oncology, Magee-Womens Hospital, Pittsburgh, PA
    • ,
  • Sushil Beriwal

      Affiliations

    • Department of Radiation Oncology, Magee-Womens Hospital, Pittsburgh, PA
    • Corresponding Author InformationCorresponding author. Department of Radiation Oncology, Magee-Womens Hospital, 300 Halket Street, Pittsburgh, PA 15213, USA. Tel.: +1-412-641-4600; fax: +1-412-641-6601.
    • ,
  • Dwight E. Heron

      Affiliations

    • Department of Radiation Oncology, Magee-Womens Hospital, Pittsburgh, PA
    • ,
  • Hayeon Kim

      Affiliations

    • Department of Radiation Oncology, Magee-Womens Hospital, Pittsburgh, PA
    • ,
  • Jeffrey Falk

      Affiliations

    • Department of Surgery, Magee-Womens Hospital, Pittsburgh, PA
    • ,
  • Ronald Johnson

      Affiliations

    • Department of Surgery, Magee-Womens Hospital, Pittsburgh, PA
    • ,
  • Robert Mogus

      Affiliations

    • Department of Radiation Oncology, Magee-Womens Hospital, Pittsburgh, PA

Received 23 May 2008 ,Revised 23 July 2008 ,Accepted 24 July 2008.

References 

  1. Bhatnagar AK, Heron DE, Deutsch M, et al. Does breast size affect the scatter dose to the ipsilateral lung, heart, or contralateral breast in primary breast irradiation using intensity-modulated radiation therapy?. Am J Clin Oncol. 2006;29:80–84
  2. Arthur D. Accelerated partial breast irradiation: a change in treatment paradigm for early breast cancer. J Surg Oncol. 2003;84:185–191
  3. Kuerer HM, Julian TB, Strom EA, et al. Accelerated partial breast irradiation after conservative surgery for breast cancer. Ann Surg. 2004;239:338–351
  4. Arthur DW, Vicini FA. Accelerated partial breast irradiation as a part of breast conservation therapy. J Clin Oncol. 2005;23:1726–1735
  5. Keisch M, Vicini F, Kuske RR, et al. Initial clinical experience with the MammoSite® breast brachytherapy applicator in women with early-stage breast cancer treated with breast-conserving therapy. Int J Radiat Oncol Biol Phys. 2003;55:289–293
  6. Kuske RR, Winter K, Arthur D, et al. A phase II trial of brachytherapy alone following lumpectomy for stage I or II breast cancer: initial outcomes of RTOG 95-17. Am J Clin Oncol. 2004;23:18
  7. King TA, Bolton JS, Kuske RR, et al. Long-term results of wide-field brachytherapy as the sole method of radiation therapy after segmental mastectomy for T(is,1,2) breast cancer. Am J Surg. 2000;180:299–304
  8. Ott OJ, Hildebrandt G, Potter R, et al. Accelerated partial breast irradiation with multi-catheter brachytherapy: local control, side effects and cosmetic outcome for 274 patients: results of the German-Austrian multi-centre trial. Radiother Oncol. 2007;82:281–286
  9. Polgar C, Fodor J, Major T, et al. Breast-conserving treatment with partial or whole breast irradiation for low-risk invasive breast carcinoma—5-year results of a randomized trial. Int J Radiat Oncol Biol Phys. 2007;69:694–702
  10. Chao K, Vicini F, Wallace M. Analysis of treatment efficacy, cosmesis, and toxicity using the MammoSite® breast brachytherapy catheter to deliver accelerated partial-breast irradiation: the William Beaumont Hospital experience. Int J Radiat Oncol Biol Phys. 2007;69:32–40
  11. Chen S, Dickler A, Kirk M. Patterns of failure after MammoSite® brachytherapy partial breast irradiation: a detailed analysis. Int J Radiat Oncol Biol Phys. 2007;69:25–31
  12. Evans S, Kaufman S, Price L. Persistent seroma after intraoperative placement of MammoSite® for accelerated partial breast irradiation: incidence, pathologic anatomy, and contributing factors. Int J Radiat Oncol Biol Phys. 2006;65:333–339
  13. Lovey K, Fodor J, Major T, et al. Fat necrosis after partial-breast irradiation with brachytherapy or electron radiation versus standard whole-breast radiotherapy—4-year results of a randomized trial. Int J Radiat Oncol Biol Phys. 2007;69:724–731
  14. Kaufman SA, Dipetrillo TA, Price LL, et al. Long-term outcome and toxicity in a Phase I/II trial using high-dose-rate multicatheter interstitial brachytherapy for T1/T2 breast cancer. Brachytherapy. 2007;6:286–292
  15. Patel R, Ringwala A, Forouzannia K. Clinical fat necrosis in patients treated with multi-catheter APBI: a 3D CT-based clinical correlation. Int J Radiat Oncol Biol Phys. 2007;69:S217

 Dr. Beriwal is on the Speakers' Bureau for MammoSite®.

PII: S1538-4721(08)00602-8

doi: 10.1016/j.brachy.2008.07.005

Brachytherapy
Volume 8, Issue 1 , Pages 9-13 , January 2009

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