Brachytherapy
Volume 7, Issue 4 , Pages 310-315 , October 2008

Early breast cancer treated with conservative surgery, adjuvant chemotherapy, and delayed accelerated partial breast irradiation with high-dose-rate brachytherapy

  • Alfonso Gómez-Iturriaga

      Affiliations

    • Department of Oncology, University of Navarra, Pamplona, Navarra, Spain
    • ,
  • Luis Pina

      Affiliations

    • Department of Radiology, University of Navarra, Pamplona, Navarra, Spain
    • ,
  • Mauricio Cambeiro

      Affiliations

    • Department of Oncology, University of Navarra, Pamplona, Navarra, Spain
    • ,
  • Fernando Martínez-Regueira

      Affiliations

    • Department of Surgery, University of Navarra, Pamplona, Navarra, Spain
    • ,
  • José Manuel Aramendía

      Affiliations

    • Department of Oncology, University of Navarra, Pamplona, Navarra, Spain
    • ,
  • Oscar Fernández-Hidalgo

      Affiliations

    • Department of Oncology, University of Navarra, Pamplona, Navarra, Spain
    • ,
  • Rafael Martínez-Monge

      Affiliations

    • Department of Oncology, University of Navarra, Pamplona, Navarra, Spain
    • Corresponding Author InformationCorresponding author. Department of Oncology, Clínica Universitaria de Navarra, University of Navarra, Avda Pío XII s/n, Pamplona, Navarra, Spain. Tel.: +1-34-948-255400; fax: +1-34-948-255500.

Received 4 February 2008 ,Revised 17 April 2008 ,Accepted 18 April 2008.

References 

  1. Arthur DW, Koo D, Zwicker RD, et al. Partial breast brachytherapy after lumpectomy: Low-dose-rate and high-dose-rate experience. Int J Radiat Oncol Biol Phys. 2003;56:681–689
  2. Benitez PR, Chen PY, Vicini FA, et al. Partial breast irradiation in breast conserving therapy by way of interstitial brachytherapy. Am J Surg. 2004;188:355–364
  3. Chen PY, Vicini FA, Benitez P, et al. Long-term cosmetic results and toxicity after accelerated partial-breast irradiation: A method of radiation delivery by interstitial brachytherapy for the treatment of early-stage breast carcinoma. Cancer. 2006;106:991–999
  4. King TA, Bolton JS, Kuske RR, et al. Long-term results of wide-field brachytherapy as the sole method of radiation therapy after segmental mastectomy for T(is,1,2) breast cancer. Am J Surg. 2000;180:299–304
  5. Kuske RR, Winter K, Arthur DW, et al. Phase II trial of brachytherapy alone after lumpectomy for select breast cancer: Toxicity analysis of RTOG 95-17. Int J Radiat Oncol Biol Phys. 2006;65:45–51
  6. Ott OJ, Hildebrandt G, Potter R, et al. Accelerated partial breast irradiation with multi-catheter brachytherapy: Local control, side effects and cosmetic outcome for 274 patients. Results of the German-Austrian multi-centre trial. Radiother Oncol. 2007;82:281–286
  7. Polgar C, Major T, Fodor J, et al. High-dose-rate brachytherapy alone versus whole breast radiotherapy with or without tumor bed boost after breast-conserving surgery: Seven-year results of a comparative study. Int J Radiat Oncol Biol Phys. 2004;60:1173–1181
  8. Polgar C, Strnad V, Major T. Brachytherapy for partial breast irradiation: The European experience. Semin Radiat Oncol. 2005;15:116–122
  9. Wazer DE, Berle L, Graham R, et al. Preliminary results of a phase I/II study of HDR brachytherapy alone for T1/T2 breast cancer. Int J Radiat Oncol Biol Phys. 2002;53:889–897
  10. NCCN Clinical Practice Guidelines in Oncology. Internet. Apr 17, 2008.
  11. Fiets WE, van Helvoirt RP, Nortier JW, et al. Acute toxicity of concurrent adjuvant radiotherapy and chemotherapy (CMF or AC) in breast cancer patients. A prospective, comparative, non-randomised study. Eur J Cancer. 2003;39:1081–1088
  12. Recht A, Come SE, Henderson IC, et al. The sequencing of chemotherapy and radiation therapy after conservative surgery for early-stage breast cancer. N Engl J Med. 1996;334:1356–1361
  13. Bellon JR, Come SE, Gelman RS, et al. Sequencing of chemotherapy and radiation therapy in early-stage breast cancer: Updated results of a prospective randomized trial. J Clin Oncol. 2005;23:1934–1940
  14. Arthur DW, Vicini FA, Kuske RR, et al. Accelerated partial breast irradiation: An updated report from the American Brachytherapy Society. Brachytherapy. 2003;2:124–130
  15. Connolly JL, Boyages J, Nixon AJ, et al. Predictors of breast recurrence after conservative surgery and radiation therapy for invasive breast cancer. Mod Pathol. 1998;11:134–139
  16. Schnitt SJ, Connolly JL, Harris JR, et al. Pathologic predictors of early local recurrence in Stage I and II breast cancer treated by primary radiation therapy. Cancer. 1984;53:1049–1057
  17. Cox JD, Stetz J, Pajak TF. Toxicity criteria of the Radiation Therapy Oncology Group (RTOG) and the European Organization for Research and Treatment of Cancer (EORTC). Int J Radiat Oncol Biol Phys. 1995;31:1341–1346
  18. Kaplan EL, Meier P. Non parametric estimation from incomplete observations. J Am Stat Assoc. 1958;53:457–481
  19. Buchholz TA, Austin-Seymour MM, Moe RE, et al. Effect of delay in radiation in the combined modality treatment of breast cancer. Int J Radiat Oncol Biol Phys. 1993;26:23–35
  20. Huang J, Barbera L, Brouwers M, et al. Does delay in starting treatment affect the outcomes of radiotherapy? A systematic review. J Clin Oncol. 2003;21:555–563
  21. Recht A, Come SE, Gelman RS, et al. Integration of conservative surgery, radiotherapy, and chemotherapy for the treatment of early-stage, node-positive breast cancer: Sequencing, timing, and outcome. J Clin Oncol. 1991;9:1662–1667
  22. Leonard CE, Wood ME, Zhen B, et al. Does administration of chemotherapy before radiotherapy in breast cancer patients treated with conservative surgery negatively impact local control?. J Clin Oncol. 1995;13:2906–2915
  23. Vujovic O, Perera F, Dar AR, et al. Does delay in breast irradiation following conservative breast surgery in node-negative breast cancer patients have an impact on risk of recurrence?. Int J Radiat Oncol Biol Phys. 1998;40:869–874
  24. Vicini FA, Kestin L, Chen P, et al. Limited-field radiation therapy in the management of early-stage breast cancer. J Natl Cancer Inst. 2003;95:1205–1210
  25. Shah NM, Tenenholz T, Arthur D, et al. MammoSite and interstitial brachytherapy for accelerated partial breast irradiation: Factors that affect toxicity and cosmesis. Cancer. 2004;101:727–734

PII: S1538-4721(08)00600-4

doi: 10.1016/j.brachy.2008.04.006

Brachytherapy
Volume 7, Issue 4 , Pages 310-315 , October 2008

Article Tools

* Image Usage & Resolution