Brachytherapy
Volume 7, Issue 4 , Pages 336-342 , October 2008

Point vs. volumetric bladder and rectal doses in combined intracavitary-interstitial high-dose-rate brachytherapy: Correlation and comparison with published Vienna applicator data

  • Ravindra Yaparpalvi

      Affiliations

    • Department of Radiation Oncology, Montefiore Medical Center and The Albert Einstein College of Medicine, Bronx, NY
    • Corresponding Author InformationCorresponding author. Department of Radiation Oncology, Montefiore Medical Center, 111 E 210th Street, Bronx, NY 10467, USA. Tel.: +1-718-920-7750; fax: +1-718-882-6914.
    • ,
  • Subhakar Mutyala

      Affiliations

    • Department of Radiation Oncology, Montefiore Medical Center and The Albert Einstein College of Medicine, Bronx, NY
    • ,
  • Giridhar R. Gorla

      Affiliations

    • Comprehensive Blood and Cancer Center, Bakersfield, CA
    • ,
  • James Butler

      Affiliations

    • Maimonides Cancer Center, Brooklyn, NY
    • ,
  • Dennis Mah

      Affiliations

    • Department of Radiation Oncology, Montefiore Medical Center and The Albert Einstein College of Medicine, Bronx, NY
    • ,
  • Madhur K. Garg

      Affiliations

    • Department of Radiation Oncology, Montefiore Medical Center and The Albert Einstein College of Medicine, Bronx, NY
    • ,
  • Shalom Kalnicki

      Affiliations

    • Department of Radiation Oncology, Montefiore Medical Center and The Albert Einstein College of Medicine, Bronx, NY

Received 30 January 2007 ,Revised 2 May 2008 ,Accepted 3 May 2008.

References 

  1. International Commission on Radiation Units and Measurements (ICRU) . Dose and volume specification for reporting intracavitary therapy in gynecology, ICRU Report 38. Bethesda, MD: ICRU; 1985;
  2. Nag S, Orton C, Young D, et al. The American Brachytherapy Society survey of brachytherapy practice for carcinoma of the cervix in the United States. Gynecol Oncol. 1999;73:111–118
  3. Potter R, Limbergen EV, Gerstner N, et al. Survey of the use of ICRU 38 in recording and reporting cervical cancer brachytherapy. Radiother Oncol. 2001;58:11–18
  4. Nag S. Controversies and new developments in gynecologic brachytherapy: Image based intracavitary brachytherapy for cervical carcinoma. Semin Radiat Oncol. 2006;16:164–167
  5. Haie-Meder C, Potter R, Van Limbergen E, et al. Recommendations from gynecological (GYN) GEC ESTRO Working Group (I): Concepts and terms in 3D image based 3D treatment planning in cervix cancer brachytherapy with emphasis on MRI assessment of GTV and CTV. Radiother Oncol. 2005;74:235–245
  6. Lang S, Nulens A, Briot E, et al. Intercomparison of treatment concepts for MR image assisted brachytherapy of cervical carcinoma based on GYN GEC-ESTRO recommendations. Radiother Oncol. 2006;78:185–193
  7. Potter R, Haie-Meder C, Van Limbergen E, et al. Recommendations from gynecological (GYN) GEC ESTRO Working Group (II): Concepts and terms in 3D image based treatment planning in cervix cancer brachytherapy—3D dose volume parameters and aspects of 3D image-based anatomy, radiation physics, radiobiology. Radiother Oncol. 2006;78:67–77
  8. Wolfson AH. Magnetic resonance imaging and positron-emission tomography imaging in the 21st century as tools for the evaluation and management of patients with invasive cervical carcinoma. Semin Radiat Oncol. 2006;16:186–191
  9. Barillot I, Horiot JC, Maingon P, et al. Maximum and mean bladder dose defined by ultrasonography. Comparison with the ICRU reference in gynecological brachytherapy. Radiother Oncol. 1994;30:231–238
  10. Kapp KS, Stueckschweiger GF, Kapp DS, et al. Dosimetry of intracavitary placements for uterine and cervical carcinoma: Results of orthogonal film, TLD, and CT-assisted techniques. Radiother Oncol. 1992;24:137–146
  11. Kim RY, Pareek P. Radiography-based treatment planning compared with computed tomography (CT)-based treatment planning for intracavitary brachytherapy in the cancer of the cervix: Analysis of dose-volume histograms. Brachytherapy. 2003;2:200–206
  12. Ling CC, Shell MC, Working KR, et al. CT-assisted assessment of the bladder and rectum dose in gynecological implants. Int J Radiat Oncol Biol Phys. 1987;13:1577–1582
  13. Pelloski CE, Palmer M, Chronowski GM, et al. Comparison between CT-based volumetric calculations and ICRU reference-point estimates of radiation doses delivered to bladder and rectum during intracavitary radiotherapy for cervical cancer. Int J Radiat Oncol Biol Phys. 2005;62:131–137
  14. Schoeppel SL, LaVigne ML, Martel MK, et al. Three-dimensional treatment planning of intracavitary gynecologic implants: Analysis of ten cases and implications for dose specification. Int J Radiat Oncol Biol Phys. 1994;28:277–283
  15. Wachter-Gerstner N, Wachter S, Reinstadler E, et al. Bladder and rectum dose defined from MRI based treatment planning for cervix cancer brachytherapy: Comparison of dose-volume histograms for organ contours and organ wall, comparison with ICRU rectum and bladder reference point. Radiother Oncol. 2003;68:269–276
  16. Datta NR, Srivastava A, Maria Das KJ, et al. Comparative assessment of doses to tumor, rectum and bladder as evaluated by orthogonal radiographs vs computer Enhanced computed tomography—based intracavitary brachytherapy in cervical cancer. Brachytherapy. 2006;5:223–229
  17. Kuipers TJ, Visser AG. Technical aspects of bladder dosimetry in intracavitary irradiation of cervix carcinoma. Radiother Oncol. 1987;7:7–12
  18. Lahtinen T, Tenhunen M, Vayrynen M. ICRU reference points and maximum doses of rectum and bladder in intracavitary radiotherapy. Radiother Oncol. 1993;28:174–176
  19. Hunter R, Wong F, Moore C, et al. Bladder base dosage in patients undergoing intracavitary therapy. Radiother Oncol. 1986;7:189–197
  20. Deshpande D, Shrivatsav S, Pradhan A, et al. Dosimetry of intracavitary applications in carcinoma of the cervix: Rectal dose analysis. Radiother Oncol. 1997;42:163–166
  21. Kessaris N, Nori D. Rectal thermoluminiscent dosimeter measurements using the microselectron high dose rate remote after loader in postoperative intravaginal radiation cases. Int J Radiat Oncol Biol Phys. 1993;26:341–345
  22. Kim RY, Jun Duan SS. Image-based three-dimensional treatment planning of intracavitary brachytherapy for cancer of the cervix: Dose-volume histograms of the bladder, rectum, sigmoid colon, and small bowel. Brachytherapy. 2007;6:187–194
  23. Fellner C, Potter R, Knocke TH, et al. Comparison of radiography and computed tomography-based treatment planning in cervix cancer in brachytherapy with specific attention to some quality assurance aspects. Radiother Oncol. 2001;58:53–62
  24. Kirisits C, Potter R, Lang S, et al. Dose and volume parameters for MRI-based treatment planning in intracavitary brachytherapy for cervical cancer. Int J Radiat Oncol Biol Phys. 2005;62:901–911
  25. Nag S, Erickson B, Thomasden B, et al. The American brachytherapy society recommendations for high-dose rate brachytherapy for carcinoma of the cervix. Int J Radiat Oncol Biol Phys. 2000;48:201–211
  26. Kirisits C, Lang S, Dimopoulos JCA, et al. The Vienna Applicator for combined intracavitary and interstitial brachytherapy of cervical cancer: Design, application, treatment planning, and dosimetric results. Int J Radiat Oncol Biol Phys. 2006;65:624–630
  27. Dimopoulos JCA, Kirisits C, Petric P, et al. The Vienna Applicator for combined intracavitary and interstitial brachytherapy of cervical cancer: Clinical feasibility and preliminary results. Int J Radiat Oncol Biol Phys. 2006;66:83–90
  28. Agrawal PP, Singhal SS, Neema JP, et al. The role of interstitial brachytherapy using template in locally advanced gynecological malignancies. Gynecol Oncol. 2005;99:169–175
  29. Demanes DJ, Rodriguez RR, Bendre DD, et al. High dose rate transperineal interstitial brachytherapy for cervical cancer: High pelvic control and low complication rates. Int J Radiat Oncol Biol Phys. 1999;45:105–112
  30. Monk BJ, Krishnansu T, Burger RA, et al. A comparison of intracavitary versus interstitial irradiation in the treatment of cervical cancer. Gynecol Oncol. 1997;67:241–247
  31. Nag S, Rafael MM, Alberto ES, et al. Interstitial brachytherapy in the management of primary carcinoma of the cervix and vagina. Gynecol Oncol. 1998;70:27–32
  32. Nath R, Anderson LL, Luxton G, et al. for the AAPM. Dosimetry of interstitial brachytherapy sources: Recommendations of the AAPM Radiation Therapy Committee Task Group no. 43. Med Phys. 1995;22:209–234
  33. Steggerda MJ, Moonen LMF, Damen EMF, et al. An analysis of the effect of ovoid shields in a selectron-LDR cervical applicator on dose distribution in rectum and bladder. Int J Radiat Oncol Biol Phys. 1997;39:237–245
  34. Van den Bergh F, Meertens H, Moonen LMF, et al. The use of a transverse CT image for the estimation of the dose given to the rectum in intracavitary brachytherapy for carcinoma of the cervix. Radiother Oncol. 1998;47:85–90
  35. Kirists C, Siebert FA, Baltas D, et al. Accuracy of volume and DVH parameters determined with different brachytherapy treatment planning systems. Radiother Oncol. 2007;84:290–297
  36. Pourquier H, Dubois JB, Delard R. Cancer of the uterine cervix: Dosimetric guidelines for prevention of late rectal and sigmoid complications as a result of radio therapeutic treatment. Int J Radiat Oncol Biol Phys. 1982;8:1887–1895
  37. Stryker JA, Bartholomew M, Velkeley DE, et al. Bladder and rectal complications following radiotherapy for cervical cancer. Gynecol Oncol. 1988;29:1–11
  38. Montana GS, Fowler WC. Carcinoma of the cervix: Analysis of bladder and rectal radiation dose and complications. Int J Radiat Oncol Biol Phys. 1989;16:95–100
  39. Chen MS, Lin FJ, Hong CH, et al. High-dose rate afterloading technique in the radiation treatment of uterine cervical cancer: 399 cases and 9 years experience in Taiwan. Int J Radiat Oncol Biol Phys. 1991;20:915–919
  40. Ongino I, Kitamura T, Okamoto N, et al. Late rectal complications following high dose rate intracavitary brachytherapy in cancer of the cervix. Int J Radiat Oncol Biol Phys. 1995;31:725–734
  41. Clark B, Souhami L, Roman TN, et al. The prediction of late rectal complications in patients treated with high dose rate brachytherapy for carcinoma of the cervix. Int J Radiat Oncol Biol Phys. 1997;38:989–993
  42. Shin KH, Huh SJ, Chie EK, et al. Analysis of correlation between rectal complications and rectal dose following high dose rate intracavitary radiotherapy in patients with uterine cervix cancer: In vivo dosimetric analysis. Radiat Med. 1999;17:289–293
  43. Ferrigno R, Santos Novaes PER, et al. High-dose-rate brachytherapy in the treatment of uterine cervix cancer. Analysis of dose effectiveness and late complications. Int J Radiat Oncol Biol Phys. 2001;50:1123–1135
  44. Katz A, Eifel PJ. Quantification of intracavitary brachytherapy parameters and correlation with outcome in patients with carcinoma of the cervix. Int J Radiat Oncol Biol Phys. 2000;48:1417–1425
  45. Chen SW, Liang JA, Yeh LS, et al. Comparative study of reference points by dosimetric analyses for late complications after uniform external radiotherapy and high-dose rate brachytherapy for cervical cancer. Int J Radiat Oncol Biol Phys. 2004;60:663–671
  46. Koom WS, Sohn DK, Kim JY, et al. Computed tomography-based high-dose rate intracavitary brachytherapy for uterine cervical cancer: Preliminary demonstration of correlation between dose-volume parameters and rectal mucosal changes observed by flexible sigmoidoscopy. Int J Radiat Oncol Biol Phys. 2007;68:1446–1454
  47. Potter R, Dimopoulos J, Bachtiary B, et al. 3D Conformal HDR-brachy- and external beam therapy plus simultaneous Cisplatin for high-risk cervical cancer: Clinical experience with 3-year follow-up. Radiother Oncol. 2006;79:80–86
  48. Huang EY, Lin H, Hsu HC, et al. High external parametrial dose can increase the probability of radiation proctitis in patients with uterine cervix cancer. Gynecol Oncol. 2000;79:406–410

PII: S1538-4721(08)00598-9

doi: 10.1016/j.brachy.2008.05.005

Brachytherapy
Volume 7, Issue 4 , Pages 336-342 , October 2008

Article Tools

* Image Usage & Resolution