Brachytherapy
Volume 7, Issue 1 , Pages 22-28 , January 2008

The feasibility of a second lumpectomy and breast brachytherapy for localized cancer in a breast previously treated with lumpectomy and radiation therapy for breast cancer

  • Manjeet Chadha

      Affiliations

    • Corresponding Author InformationCorresponding author. Department of Radiation Oncology, Beth Israel Medical Center, 10 Union Square East, New York, NY 10003. Tel.: +1-212-844-8022; fax: +1-212-844-6556.
    • ,
  • Sheldon Feldman

      Affiliations

    • Department of Surgery, Beth Israel Medical Center, New York, NY
    • ,
  • Susan Boolbol

      Affiliations

    • Department of Surgery, Beth Israel Medical Center, New York, NY
    • ,
  • Lin Wang

      Affiliations

    • Department of Radiation Oncology, Beth Israel Medical Center, New York, NY
    • ,
  • Louis B. Harrison

      Affiliations

    • Department of Radiation Oncology, Beth Israel Medical Center, New York, NY

Received 19 June 2007 ,Accepted 12 October 2007.

References 

  1. Salvadori B, Marubini E, Miceli R, et al. Reoperation for locally recurrent breast cancer in patients previously treated with conservative surgery. Br J Surg. 1999;86:84–87
  2. Kurtz JM, Jacquemier J, Amalric R, et al. Is breast conservation after local recurrence feasible?. Eur J Cancer. 1991;27(3):24–244
  3. Abner AL, Recht A, Eberlein T, et al. Prognosis following salvage mastectomy for recurrence in the breast after conservative surgery and radiation therapy for early-stage breast cancer. J Clin Oncol. 1993;11:44–48
  4. Voogd AC, Tienhoven G, Peterse HL, et al. Local recurrence after breast conservation therapy for early stage breast carcinoma. Cancer. 1999;85:437–446
  5. Dalberg K, Mattson A, Kerstin S, et al. Outcome of treatment for ipsilateral breast tumor recurrence in early-stage breast cancer. Breast Cancer Res Treat. 1998;49:69–78
  6. Kuske RR, Bolton JS, Wilenzick RM, et al. Brachytherapy as the sole method of breast irradiation in Tis, T1, t2 N0-1 breast cancer. Int J Radiat Oncol Biol Phys. 1994;30(s1):245
  7. Vicini FA, Chen PY, Fraile M, et al. Low-dose-rate brachytherapy as the sole radiation modality in the management of patients with early-stage breast cancer treated with breast conserving therapy: Preliminary results of a pilot trial. Int J Radiat Oncol Biol Phys. 1997;38:301–310
  8. Nag S, Kuske RR, Vicini FA, et al. Brachytherapy in the treatment of breast cancer. Oncology (Huntingt). 2001;15:195–202
  9. Baglan KL, Martinez AA, Frazier RC, et al. The use of high dose-rate brachytherapy alone after lumpectomy in patients with early-stage breast cancer treated with breast-conserving therapy. Int J Radiat Oncol Biol Phys. 2001;50:1003–1011
  10. Polgar C, Major T, Fodor J, et al. High-dose rate brachytherapy alone versus whole breast radiotherapy with or without tumor bed boost after breast-conserving surgery: Seven-year results of a comparative study. Int J Radiat Oncol Biol Phys. 2004;60:1173–1181
  11. Wallner P, Arthur D, Bartelink H, et al. Workshop on partial breast irradiation: State of the art and the science, Bethesda, MD, December 8–10, 2002. J Natl Cancer Inst. 2004;96:175–184
  12. Cancer Therapy Evaluation Program: Common Terminology Criteria for Adverse Events, Version 3.0, DCTD, NCI, NIH, DHHS. Available at: http://ctep.cancer.gov/reporting/ctc_v30.htmlAugust 9, 2006;
  13. Fisher B, Anderson S, Bryant J, et al. Twenty-year follow-up of a randomized trial comparing total mastectomy, lumpectomy, and lumpectomy plus irradiation for the treatment of invasive breast cancer. N Engl J Med. 2002;347(16):1233–1241
  14. Veronesi U, Cascinelli N, Mariani L, et al. Twenty-year follow-up of a randomized study comparing breast-conserving surgery with radical mastectomy for early breast cancer. N Engl J Med. 2002;347(16):1227–1232
  15. Kurtz JM, Amalric R, Brandone H, et al. Local recurrence after breast conserving surgery and radiotherapy. Cancer. 1995;75:1310–1319
  16. Osborne MP, Simmons RM. Salvage surgery for recurrence after breast conservation. World J Surg. 1994;18(1):93–97
  17. Huston TL, Simmons RM. Locally recurrent breast cancer after conservation therapy. Am J Surg. 2005;189(2):229–235
  18. Stotter AS, Kroll S, McNeese M, et al. Salvage treatment for locoregional recurrence following breast conservation therapy for early stage breast cancer. Eur J Surg Oncol. 1991;17(3):231–236
  19. Kennedy MJ, Abeloff MD. Management of locally recurrent breast cancer. Cancer. 1993;71:2395–2409
  20. Osborne MP. Salvage mastectomy. Semin Surg Oncol. 1991;7:291–295
  21. Osborne MP, Borgen PI, Wong GY, et al. Salvage mastectomy for local and regional recurrence after breast conserving operation and radiation therapy. Surg Gynecol Obstet. 1992;174:89–194
  22. Drew PJ, Kerin MJ, Turnbull LW, et al. Routine screening for local recurrence following breast conserving therapy for cancer with dynamic contrast—Enhanced magnetic resonance imaging of the breast. Ann Surg Oncol. 1998;5:265–270
  23. Emami B, Lyman J, Brown A, et al. Tolerance of normal tissue to therapeutic irradiation. Int J Radiat Oncol Biol Phys. 1991;21:109–122
  24. Zelefsky MJ, Leibel SA, Gaudin PB, et al. Dose escalation with three-dimensional conformal radiation therapy affects the outcome in prostate cancer. Int J Radiat Oncol Biol Phys. 1998;41:491–500
  25. Rosenzweig KE, Fox JL, Yorke E, et al. Results of a phase I dose escalation study using 3-dimensional conformal radiotherapy in the treatment of inoperable nonsmall cell lung carcinoma. Cancer. 2005;103:2118–2127
  26. Benitez PR, Chen PY, Vicini FA, et al. Partial breast irradiation in breast conserving therapy by way of interstitial brachytherapy. Am J Surg. 2004;188:355–364
  27. Chen PY, Vicini FA, Benitez P, et al. Long-term cosmetic results and toxicity after accelerated partial-breast irradiation. Cancer. 2006;106:991–999
  28. Ott OJ, Hildebrandt G, Potter R, et al. Accelerated partial breast irradiation with multi-catheter brachytherapy: Local control, side effects and cosmetic outcome for 274 patients. Results of the German–Austrian multi-centre trial. Radiother Oncol. 2006;
  29. Arthur DW, Winter K, Kuske RR, et al. A phase II trial of brachytherapy alone following lumpectomy for select breast cancer: Tumor control and survival outcomes of RTOG 95-17. (Abstr. 51) Int J Radiat Oncol Biol Phys. 2006;66(Suppl.):S29–S30
  30. National Surgical Adjuvant Breast and Bowel Project B-39/Radiation Therapy Oncology Group 0413 Protocol . Available at: http://www.rtog.org/members/protocols/0413/0413.pdfAccessed February 7, 2008
  31. Solin LJ, Fourquet A, Vicini F, et al. Salvage treatment for local recurrence after breast conserving surgery and radiation as initial treatment for mammographically detected ductal carcinoma in situ of the breast. Cancer. 2001;91:1090–1097
  32. Fortin A, Larochelle M, Laverdiere J, et al. Local failure is responsible for the decrease in survival of patients with breast cancer treated with conservative surgery and postoperative radiotherapy. J Clin Oncol. 1999;17:101–109
  33. Recht A, Schnitt SJ, Connolly JL, et al. Prognosis following local or regional recurrence after conservative surgery and radiotherapy for early stage breast carcinoma. Int J Radiol Biol Phys. 1989;16:3–9
  34. Gage I, Scnitt SJ, Recht A, et al. Skin recurrences after breast conserving therapy for early stage breast cancer. J Clin Oncol. 1998;16:480–486
  35. Kurtz J, Spitalier J, Amalric R. The prognostic significance of late local recurrence after breast-conserving therapy. Int J Radiat Oncol Biol Phys. 1990;18:87
  36. Obedian E, Fischer DB, Haffty BG. Second malignancies after treatment of early stage breast cancer: Lumpectomy and radiation therapy versus mastectomy. J Clin Oncol. 2000;18:2406–2412
  37. Smith TE, Lee D, Turner BC, et al. True recurrence vs. new ipsilateral breast tumor relapse: An analysis of clinical and pathologic differences and their implications in natural history, prognoses, and therapeutic management. Int J Radiat Oncol Biol Phys. 2000;48:1281–1289
  38. Veronesi U, Marubini E, Del Vecchio M, et al. Local recurrences and distant metastases after conservative breast cancer treatments; partly independent events. J Natl Cancer Inst. 1995;87:19–27
  39. Huang E, Buchholtz TA, Meric F, et al. Classifying local disease recurrences after breast conservation therapy based on location and histology. Cancer. 2002;95:2059–2067
  40. Haffty BG, Fischer D, Beinfield M, et al. Prognosis following local recurrence in the conservatively treated breast cancer patient. Int J Radiat Oncol Biol Phys. 1991;21:293–298
  41. Vicini FA, Beitsch PD, Quiet CA, et al. First analysis of patient demographics, technical reproducibility cosmesis and early toxicity—Results of the ASBS Mammosite breast brachytherapy registry trial. Cancer. 2005;104:1138–1148
  42. Hannoun-Levi J, Houvenaeghel G, Ellis S, et al. Partial breast irradiation as second conservative treatment for local breast cancer recurrence. Int J Radiat Oncol Biol Phys. 2004;60(5):1385–1392
  43. Maingon P, Jolicoeur M, D'Hombres A, et al. Perioperative interstitial brachytherapy for salvage of breast conservation therapy recurrences. Proceedings of ARS; 1999.
  44. Maulard C, Housset M, Brunel P, et al. Use of perioperative or split-course interstitial brachytherapy techniques for salvage irradiation of isolated local recurrences after conservative management of breast cancer. Am J Clin Oncol. 1995;18(4):348–352
  45. Resch A, Fellner C, Mock U, et al. Locally recurrent breast cancer: Pulse dose rate brachytherapy for repeat irradiation following lumpectomy—A second chance to preserve the breast. Radiology. 2002;225:713–718
  46. Deutsch M. Repeat high-dose external beam irradiation for in-breast tumor recurrence after previous lumpectomy and whole breast irradiation. Int J Radiat Oncol Biol Phys. 2002;53(3):687–691

 Presented in part at the 48th Annual Meeting of the American Society of Radiology and Oncology, Philadelphia 2006.

 The authors of this article have no conflict of interest with the material presented in this manuscript.

PII: S1538-4721(07)00285-1

doi: 10.1016/j.brachy.2007.10.006

Brachytherapy
Volume 7, Issue 1 , Pages 22-28 , January 2008

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