Brachytherapy
Volume 7, Issue 1 , Pages 29-36 , January 2008

Breast conservation surgery and interstitial brachytherapy in the management of locally recurrent carcinoma of the breast: The Allegheny General Hospital experience

  • Mark Trombetta

      Affiliations

    • Department of Radiation Oncology, Allegheny General Hospital, Pittsburgh, PA
    • Corresponding Author InformationCorresponding author. Department of Radiation Oncology, Allegheny General Hospital, 320 East North Avenue, Pittsburgh, PA 15212, USA. Tel.: +1-412-359-3400; fax: +1-412-359-3981.
    • ,
  • Thomas Julian

      Affiliations

    • Department of Human Oncology, Allegheny General Hospital, Pittsburgh, PA
    • ,
  • Tanuja Bhandari

      Affiliations

    • Department of Radiation Oncology, Allegheny General Hospital, Pittsburgh, PA
    • ,
  • E. Day Werts

      Affiliations

    • Department of Radiation Oncology, Allegheny General Hospital, Pittsburgh, PA
    • ,
  • Moyed Miften

      Affiliations

    • Department of Radiation Oncology, Allegheny General Hospital, Pittsburgh, PA
    • ,
  • David Parda

      Affiliations

    • Department of Radiation Oncology, Allegheny General Hospital, Pittsburgh, PA

Received 13 September 2007 ,Revised 27 November 2007 ,Accepted 5 December 2007.

References 

  1. Jemal A, Siegel R, Ward E, et al. Cancer statistics, 2007. CA Cancer J Clin. 2007;57:43–66
  2. Glass A, Lacey J, Carreon J, et al. Breast cancer incidence, 1980–2006: Combined roles of menopausal hormone therapy, screening mammography, and estrogen receptor status. J Natl Cancer Inst. 2007;99:1152–1161
  3. Fisher B, Dignam J, Bryant J, et al. Five versus more than five years of tamoxifen for lymph node-negative breast cancer: Updated findings from the National Surgical Adjuvant Breast and Bowel Project B-14 randomized trial. J Natl Cancer Inst. 2001;93(May 2):684–690
  4. Fisher B, Costantino JP, Wickerham DL, et al. Tamoxifen for prevention of breast cancer: Report of the National Surgical Adjuvant Breast and Bowel Project P-1 Study. J Natl Cancer Inst. 1998;90:1371–1388
  5. Fisher B, Bauer M, Margolese R, et al. Five year results of a randomized clinical trial comparing total mastectomy and segmental mastectomy with or without radiation in the treatment of breast cancer. N Engl J Med. 1985;312:665–673
  6. Veronesi U, Saccozzi R, Del Vecchio M, et al. Comparing radical mastectomy with quadrantectomy, axillary dissection, and radiotherapy in patients with small cancers of the breast. N Engl J Med. 1981;305:6–11
  7. Fowble BL, Solin LJ, Schultz DJ, et al. Ten year results of conservative surgery and irradiation for stage I and II breast cancer. Int J Radiat Oncol Biol Phys. 1991;21:269–277
  8. Abner AL, Recht A, Eberlein T, et al. Prognosis following salvage mastectomy for recurrence in the breast after conservative surgery and radiation therapy for early-stage breast cancer. J Clin Oncol. 1993;11:44–48
  9. NIH publ no. 94-2789 In:  Ries LAG,  Miller BA,  Hankey BF, et al. editor. SEER Cancer statistics review, 1973–1991: tables and graphs. Bethesda: USDHHS National Cancer Institute; 1994;
  10. Ganz P, Coscarelli Schag C, Lee JJ, et al. Breast conservation versus mastectomy; is there a difference in psychological adjustment or quality of life in the year after surgery?. Cancer. 1992;69:1729–1738
  11. Maunsell E, Brisson J, Deschhes L. Psychological distress after initial treatment for breast cancer: A comparison of partial and total mastectomy. J Clin Epidemiol. 1989;42:765–771
  12. Nag S, Kuske RR, Vicini FA, et al. Brachytherapy in the treatment of breast cancer. Oncology. 2001;15:195–202
  13. Kuske RR, Winter K, Arthur D, et al. A phase II trial of brachytherapy alone following lumpectomy for select breast cancer: Toxicity analysis of RTOG 95-17. Int J Radiat Oncol Biol Phys. 2006;65(1):45–51
  14. King T, Bolton J, Kuske R, et al. Long term results of wide-field brachytherapy as the sole method of radiation therapy after segmental mastectomy for Tis,1,2 breast cancer. Am J Surg. 2000;180:299–304
  15. Baglan K, Martinez A, Frazier R, et al. The use of high-dose rate brachytherapy alone after lumpectomy in patients with early stage breast cancer treated with breast-conserving therapy. Int J Radiat Oncol Biol Phys. 2001;50(4):1003–1011
  16. Salvadori B, Marubini E, Miceli R, et al. Reoperation for locally recurrent breast cancer in patients previously treated with conservative surgery. Br J Surg. 1999;86:84–87
  17. Kurtz JM, Spitalier JM, Amalric R. Results of salvage surgery for mammary recurrence following breast conserving therapy. Ann Surg. 1988;207:347–351
  18. Komoike Y, Motomura K, Inaji H, et al. Repeat lumpectomy for patients with ipsilateral breast tumor recurrence after breast conserving surgery. Oncology. 2003;64:1–6
  19. Silverstein MJ, Poller DN, Waisman JR, et al. A prognostic index for ductal carcinoma of the breast. Cancer. 1996;77:2267–2274
  20. Huang E, Bucholz T, Meric F, et al. Classifying local disease recurrences after breast conservation therapy based on location and histology. Cancer. 2002;95(10):2059–2067
  21. Doyle T, Schultz D, Peters C, et al. Long-term results of local recurrence after breast conservation treatment for invasive breast cancer. Int J Radiat Oncol Biol Phys. 2001;51(1):74–80
  22. Cajucom C, Tsangaris T, Nemoto T, et al. Results of salvage mastectomy for local recurrence after breast-conserving surgery without radiation therapy. Cancer. 1993;57(5):1174–1779
  23. Recht A, Schnitt SJ, Connolly JL, et al. Prognosis following local or regional recurrence after conservative surgery and radiotherapy for early stage breast cancer. Int J Radiat Oncol Biol Phys. 1989;16:3–9
  24. Fowble B, Solin L, Schultz D, et al. Breast recurrence following conservative surgery and radiation: Patterns of failure, prognosis, and pathologic findings from mastectomy specimens with implications for treatment. Int J Radiat Oncol Biol Phys. 1990;19:833–842
  25. Haffty BG, Fischer D, Beinfield M, et al. Prognosis following local recurrence in the conservatively treated breast cancer patient. Int J Radiat Oncol Biol Phys. 1991;21:293
  26. Mullen E, Deutsch M, Bloomer WD, et al. Salvage radiotherapy for local failures of lumpectomy and breast irradiation. Radiother Oncol. 1997;42:25–29
  27. Deutsch M. Repeat high-dose external beam irradiation for in-breast tumor recurrence after previous lumpectomy and whole breast irradiation. Int J Radiat Oncol Biol Phys. 2002;53(3):687–691
  28. Petrovich Z, Langholz B, Lam K, et al. Interstitial microwave hyperthermia combined with Iridium-192 radiotherapy for recurrent tumors. Am J Clin Oncol. 1989;12(3):264–268
  29. Hannoun-Levi JM, Houvenaeghel G, Ellis S, et al. Partial breast irradiation as second conservative treatment for local breast cancer recurrence. Int J Radiat Oncol Biol Phys. 2004;60(5):1385–1392
  30. Rowland J, Desmond K, Meyerowitz B, et al. Role of breast reconstruction in physical and emotional outcomes among breast cancer survivors. J Natl Cancer Inst. 2000;92:1422–1429
  31. Kuerer H, Arthur D, Haffty B. Repeat breast surgery for in-breast local breast carcinoma recurrence. Cancer. 2004;100:2269–2280
  32. Keisch M, Vicini F, Kuske R, et al. Initial clinical experience with the MammoSite breast brachytherapy applicator in women with early-stage breast cancer treated with breast-conserving therapy. Int J Radiat Oncol Biol Phys. 2003;55:289–293
  33. Polgar C, Sulyok Z, Fodor J, et al. Sole brachytherapy of the tumor bed after conservative surgery for T1 breast cancer: Five-year results of a Phase I-II study and initial findings of a randomized Phase III trial. J Surg Oncol. 2002;80:121–128
  34. Perera F, Engel J, Holliday R, et al. Local resection and brachytherapy confined to the lumpectomy site for early breast cancer: A pilot study. J Surg Oncol. 1997;65:263–267
  35. Baglan KL, Sharpe MB, Jaffray D, et al. Accelerated partial breast irradiation using 3D conformal radiation therapy (3D-CRT). Int J Radiat Oncol Biol Phys. 2003;55:302–311
  36. Perera F, Chisela F, Engel J, et al. Method of localization and implantation of the lumpectomy site for high dose rate brachytherapy after conservative surgery for T1 and T2 breast cancer. Int J Radiat Oncol Biol Phys. 1995;31:959–965
  37. Vicini FA, Baglan KL, Kestin LL, et al. Accelerated treatment of breast cancer. J Clin Oncol. 2001;19:1993–2001
  38. NSABP Protocol B-39 (Radiation Therapy Oncology Group protocol 0413).
  39. NSABP Protocol B-39 Form COS.

PII: S1538-4721(07)00278-4

doi: 10.1016/j.brachy.2007.12.001

Brachytherapy
Volume 7, Issue 1 , Pages 29-36 , January 2008

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