Brachytherapy
Volume 5, Issue 3 , Pages 183-188 , July 2006

A dosimetric comparison of three-dimensional conformal, intensity-modulated radiation therapy, and MammoSite partial-breast irradiation

Received 19 May 2006 ,Revised 5 June 2006 ,Accepted 5 June 2006.

References 

  1. Veronesi U, Cascinelli N, Mariani L, et al. Twenty-year follow-up of a randomized study comparing breast-conserving surgery with radical mastectomy for early breast cancer. N Engl J Med. 2002;347:1227–1232
  2. Fisher B, Anderson S, Bryant J, et al. Twenty-year follow-up of a randomized trial comparing total mastectomy, lumpectomy, and lumpectomy plus irradiation for the treatment of invasive breast cancer. N Engl J Med. 2002;341:1233–1241
  3. Leljegren G, Holmberg L, Bergh J, et al. 10-year results after sector resection with or without postoperative radiotherapy for stage I breast cancer: A randomized trial. J Clin Oncol. 1999;17:2326–2333
  4. Clark RM, Whelan T, Levine M, et al. Randomized clinical trial of breast irradiation following lumpectomy and axillary dissection for node-negative breast cancer: An update. Ontario Clinical Oncology Group. J Natl Cancer Inst. 1996;88:1659–1664
  5. Fisher ER, Anderson S, Redmond C, et al. Ipsilateral breast tumor recurrence and survival following lumpectomy and irradiation: Pathologic findings from NSABP protocol B-06. Semin Surg Oncol. 1992;8:161–166
  6. Gage I, Recht A, Gelman R, et al. Long-term outcome following breast conserving surgery and radiation therapy. Int J Radiat Oncol Biol Phys. 1995;33:245–251
  7. Fisher ET, Sass R, Fisher B, et al. Pathologic findings from the National Surgical Adjuvant Breast Project (protocol 6). II. Relationship of local breast recurrence to multicentricity. Cancer. 1986;57:1717–1724
  8. Faverly DR, Hedriks JHCL, Holland R. Breast carcinomas of limited extent: Frequency, radiologic–pathologic characteristics, and surgical margin requirements. Cancer. 2001;91:647–659
  9. Immamura H, Haga S, Shimizu T, et al. Relationship between the morphological and biological characteristics of intraductal components accompanying invasive ductal breast carcinoma and patient age. Breast Cancer Res Treat. 2000;62:177–184
  10. Goldstein NS, Vicini F, Kestin L. Defining the clinical target volume for patients with early stage breast cancer treated with lumpectomy and accelerated partial breast irradiation: A pathological analysis. Int J Radiat Oncol Biol Phys. 2004;60:S275–S276
  11. Farrow DC, Hunt WC, Samet JM, et al. Geographic variation the treatment of localized breast cancer. N Engl J Med. 1992;326:1097–1101
  12. Dolan JT, Franchi TS, Miller CC, et al. Low use of breast conservation surgery in medically indigent populations. Am J Surg. 1999;178:470–474
  13. Vicini F, Kini VR, Chen P, et al. Irradiation of the tumor bed alone after lumpectomy in selected patients with early-stage breast cancer treated with breast conserving therapy. J Surg Oncol. 1999;70:33–40
  14. Baglan KL, Martinez AA, Frazier RC, et al. The use of high-dose rate brachytherapy alone after lumpectomy in patients with early-stage breast cancer treated with breast-conserving therapy. Int J Radiat Oncol Biol Phys. 2001;50:1003–1011
  15. Vicini FA, Kestin L, Chen P, et al. Limited-field radiation therapy in the management of early-stage breast cancer. J Natl Cancer Inst. 2003;95:1205–1211
  16. Edmundson G, Vicini F, Chen P, et al. Dosimetric characteristics of the MammoSite RTS, a new breast brachytherapy applicator. Int J Radiat Oncol Biol Phys. 2002;52:1132–1139
  17. Dickler A, Kirk M, Choo J, et al. Treatment volume and dose optimization of the MammoSite breast brachytherapy applicator. Int J Radiat Oncol Biol Phys. 2004;9:469–474
  18. Dickler A, Kirk MC, Choo J, et al. Cosmetic outcome and incidence of infection with the MammoSite breast brachytherapy applicator. Breast J. 2005;11:306–310
  19. Choo JC, Mehta PM, Nguyen CN, et al. Initial clinical results with the MammoSite breast brachytherapy applicator in women with early-stage breast cancer. Int J Radiat Oncol Biol Phys. 2005;63:S232
  20. Formenti SC, Rosenstein B, Skinner KA, et al. T1 stage breast cancer: Adjuvant hypofractionated conformal radiation therapy to tumor bed in selected postmenopausal breast cancer patients—Pilot feasibility study. Radiology. 2002;222:171–178
  21. Formenti SC, Truong MT, Goldberg JD, et al. Prone accelerated partial breast radiation (p-apbi) after breast conserving surgery: Preliminary clinical results and dose volume histogram (DVH) analysis. Int J Radiat Oncol Biol Phys. 2004;60:493–504
  22. Vicini FA, Remouchamps V, Wallace M, et al. Ongoing clinical experience utilizing 3D conformal external beam radiotherapy to deliver partial-breast irradiation in patients with early-stage breast cancer treated with breast-conserving therapy. Int J Radiat Oncol Biol Phys. 2003;57:1247–1253
  23. Lacombe MA, McMahon J, Al-Najjar WD, et al. Accelerated partial breast irradiation using intensity modulated radiotherapy. Int J Radiat Oncol Biol Phys. 2004;60:S273–S274
  24. Baglan KL, Sharpe SB, Jaffray D, et al. Accelerated partial breast irradiation using 3D conformal radiation therapy (3D-CRT). Int J Radiat Oncol Biol Phys. 2003;55:302–311
  25. Whelan T, MacKenzie R, Julian J, et al. Randomized trial of breast irradiation schedules after lumpectomy for women with lymph node-negative breast cancer. J Natl Cancer Inst. 2002;94:1143–1150
  26. Ribeiro GG, Magee B, Swindell R, et al. The Christie Hospital breast conservation trial: An update at 8 years from inception. Clin Oncol. 1993;5:278–283
  27. Weed DW, Edmundson GK, Vicini FA, et al. Accelerated partial breast irradiation: A dosimetric comparison of three different techniques. Brachytherapy. 2005;4:121–129
  28. Kirk M, Hsi WC, Dickler A, et al. Surface optimization technique for MammoSite breast brachytherapy applicator. Int J Radiat Oncol Biol Phys. 2005;62:366–372
  29. Wazer D, Lowther D, Boyle T, et al. Clinically evident fat necrosis in women treated with high-dose-rate brachytherapy alone for early-stage breast cancer. Int J Radiat Oncol Biol Phys. 2001;50:107–111
  30. Suh WW, Pierce LJ, Vicini FA, et al. A cost comparison analysis of partial versus whole-breast irradiation after breast conserving surgery for early-stage breast cancer. Int J Radiat Oncol Biol Phys. 2005;62:790–796

 These data were presented as poster/discussion at ASTRO 2005.Financial disclosure: Dr. Adam Dickler is a member of the clinical training faculty for Cytyc Corporation, Marlborough, MA.

PII: S1538-4721(06)00201-7

doi: 10.1016/j.brachy.2006.06.001

Brachytherapy
Volume 5, Issue 3 , Pages 183-188 , July 2006